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Titi
January 30, 2026
5.0
First time in today and very much impressed. Becca was superb! Friendly, fast, professional and knowledgeable! Genuine smile to top it all off. I will be returning for sure!
MedicalRecreational$$
Native Roots Marijuana Dispensary Santa Fe - South Denver MED/REC
4.7(1,145)
Native Roots Marijuana Dispensary Santa Fe - South Denver MED/REC is a highly-rated recreational and medical cannabis dispensary in Denver, Colorado, with a 4.7-star average across 1,145+ customer reviews. The shop carries a full selection of flower, pre-rolls, vaporizers, edibles, concentrates, tinctures, topicals, and accessories. Native Roots Marijuana Dispensary Santa Fe - South Denver MED/REC offers delivery, in-store shopping. Customers frequently mention micah was very friendly and knowledgeable in helping me find what I wanted.
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2645 South Santa Fe Drive
Denver, CO 80223
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$$ · Medical & Recreational
Save ~15%/yr with a Colorado medical card
Medical patients skip recreational taxes, get higher purchase limits, and can shop at age 18+. Most people get approved online in about 20 minutes.
Products & Menu
FlowerPre-RollsVapesEdiblesConcentratesTincturesTopicalsAccessories
THC:10%–30%
CBD:0%–20%
Features & Amenities
Experience
💻Online Ordering
Fulfillment
🚚Delivery🏪In-Store
Payment
💵Cash
Medical
🏥Accepts Medical Card
Shopper Type
🌱Beginner-Friendly
Access
♿Wheelchair Accessible
Hours
Monday9:00 AM – 11:45 PM
Tuesday9:00 AM – 11:45 PM
Wednesday9:00 AM – 11:45 PM
Thursday9:00 AM – 11:45 PM
Friday9:00 AM – 11:45 PM
Saturday(Today)9:00 AM – 11:45 PM
Sunday9:00 AM – 11:45 PM
Reviews (1145)
4.7
4.7
1,145 reviews
A
Aimee sailas
January 20, 2026
5.0
Micah was very informative and incredibly friendly. The prices were good and the atmosphere was even better. We not what we wanted even more. Thank you Micah!
T
Terry Cannon
January 16, 2026
5.0
Micah was very friendly and knowledgeable in helping me find what I wanted. I love the convenience of the store, right on Santa Fe. They have a great web site where you can order in advance. They give me a veteran's discount and they have other rewards.
R
Rachel Permenter
December 23, 2025
5.0
My budtender was Sebastian! He was friendly and knowledgeable. Made a quick stop here being from Texas, I had been to another location in Frisco so stopped at this location. Glad I did! He made my weekend in Denver and the mountains enjoyable! Thanks so much!
C
Charlotte Stien
December 4, 2025
5.0
Jen was absolutely amazing, she had such a huge variety that she let me choose from and made the process so smooth and easy. It was my first time at this dispensary today and Jen was just an absolute marvel, she helped me find exactly what I needed for exactly the amount I wanted to spend. You couldn’t ask for a better person to help you out. :)
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Frequently Asked Questions About Native Roots Marijuana Dispensary Santa Fe - South Denver MED/REC
Can tourists buy from Native Roots Marijuana Dispensary Santa Fe - South Denver MED/REC?
Tourists 21+ can purchase recreational cannabis with a valid government-issued photo ID. Purchase limits are the same as residents. Cannabis cannot be taken out of state. Native Roots Marijuana Dispensary Santa Fe - South Denver MED/REC is a medical & recreational dispensary, so no medical card is needed for adult-use purchases.
How much can you buy at Native Roots Marijuana Dispensary Santa Fe - South Denver MED/REC?
In Colorado, recreational customers can purchase up to 1 oz (28g) of flower, or its equivalent in concentrates (8g) or edibles (800mg THC). Native Roots Marijuana Dispensary Santa Fe - South Denver MED/REC may have additional product-specific limits — check with the dispensary for details.
Is Native Roots Marijuana Dispensary Santa Fe - South Denver MED/REC cash only?
Native Roots Marijuana Dispensary Santa Fe - South Denver MED/REC is cash only. Check with the dispensary for nearby ATM locations.
Does Native Roots Marijuana Dispensary Santa Fe - South Denver MED/REC offer delivery?
Yes, Native Roots Marijuana Dispensary Santa Fe - South Denver MED/REC offers delivery. Cannabis delivery is legal in Colorado. Check the dispensary's website for delivery areas and minimum order requirements.
What are Native Roots Marijuana Dispensary Santa Fe - South Denver MED/REC's hours?
Native Roots Marijuana Dispensary Santa Fe - South Denver MED/REC is located at 2645 South Santa Fe Drive, Denver, CO 80223. The dispensary is open 7 days a week. Hours vary by day — check the hours section above for today's schedule.
Get Your Colorado Medical Card Online
Medical patients in Colorado save ~15% on cannabis purchases, get higher purchase limits, and access dispensaries at age 18+. Most patients can get approved online in about 20 minutes.
✓ Board-certified physicians · ✓ 4.8★ rated · ✓ 500,000+ patients approved
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Cannabis Laws in Colorado
Last updated January 15, 2026
Colorado made history as one of the first two states (alongside Washington) to legalize recreational cannabis in 2012 through Amendment 64. Adults 21+ can purchase from licensed dispensaries. Colorado also has a mature medical marijuana program dating back to 2000.
Minimum Age
Recreational: 21+
Medical: 18+
Purchase Limits
Rec: 1 oz (28g) of flower, or its equivalent in concentrates (8g) or edibles (800mg THC)
Med: 2 oz (56g) of flower per day (up to an extended plant count with physician recommendation)
Public Consumption
Prohibited in public. Colorado law prohibits consuming cannabis openly and publicly. Some licensed social consumption establishments exist in certain cities like Denver. Private property with owner permission is allowed.
Home Growing
Adults 21+ may grow up to 6 plants per person, with no more than 3 mature at a time. Maximum of 12 plants per household regardless of number of adults. Must be in an enclosed, locked space.
Delivery
Allowed
Tax Info
Recreational cannabis is subject to a 15% state excise tax on wholesale transactions plus a 15% special sales tax at retail, in addition to the 2.9% state sales tax and local taxes. Medical cannabis is exempt from the special sales tax.
Visitor & Tourist Rules
Tourists 21+ can purchase recreational cannabis with a valid government-issued photo ID. Purchase limits are the same as residents. Cannabis cannot be taken out of state.
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Disclaimer: Cannabis laws change frequently. This information was last updated on January 15, 2026. Always verify current laws with official state sources before making any decisions. This guide is for informational purposes only and does not constitute legal advice.