chris weaver
December 31, 2025
Great shop, great prices, fabulous and knowledgeable staff. Always fresh flower!

Trail's Head Cannabis Co. is a medical cannabis dispensary located in Deadwood, South Dakota, dedicated to providing quality cannabis products and education to its patients. The knowledgeable staff is committed to helping customers navigate the benefits of THC and CBD products in a safe and comfortable environment.
4.8
40 reviews
chris weaver
December 31, 2025
Great shop, great prices, fabulous and knowledgeable staff. Always fresh flower!
Crystal Nunn
December 23, 2025
By far my favorite dispensary! The store is gorgeous, the staff are very friendly and extremely knowledgeable. They have an amazing selection of cannabis related products and always have a FRESH selection of flower. I love everyone there! Great people
Vicki Strickland
December 17, 2025
I appreciate the products & people who are so knowledgeable in helping with my journey to seek pain relief and an appetite, as I suffer from wasting disease and struggle to maintain body weight.
Jake
December 15, 2025
Always a great experience at Trail’s Head Cannabis. The staff is genuinely friendly, knowledgeable, and never make you feel rushed. Clean shop, good selection, and they are happy to answer questions and help you find the right thing. Highly recommend!
Chaz Duran
February 27, 2025
I've been to this location on two occasions. Very, very beautiful decor. Deli style, which I love and the variety of strains from different growers and the option of buying it by the gram is always awesome for Sampling or variety and the prices are comparable/lower. Both Budtenders were amazing to talk with and answered my questions thoroughly. My only negative was on my first visit I got a magnificent strain, a week later returned and it was sold out due to limited quantities for freshness reasons but you can't really complain about that. I will definitely be returning.
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Levoit Core 300-P
143 CFM · 219 sq ft
$80–$110

Coway Airmega AP-1512HH
246 CFM · 361 sq ft
$160–$210

Austin Air HM400
400 CFM · 1,500 sq ft
$475–$595
Only South Dakota residents with medical cards may purchase. No out-of-state reciprocity. Trail's Head Cannabis Co. is a medical dispensary, so a valid medical card is required for purchases.
In South Dakota, medical customers can purchase up to 3 oz per calendar year (increased amounts available with physician authorization). Trail's Head Cannabis Co. may have additional product-specific limits — check with the dispensary for details.
Trail's Head Cannabis Co. is cash only. Check with the dispensary for nearby ATM locations.
Trail's Head Cannabis Co. does not currently list delivery as an option. Available options include in-store.
Trail's Head Cannabis Co. is located at 32 Charles Street, Deadwood, SD 57732. The dispensary is open 7 days a week. Hours vary by day — check the hours section above for today's schedule.
Last updated January 15, 2026
South Dakota legalized medical marijuana in 2020 through Initiated Measure 26. A simultaneous recreational measure (Amendment A) was passed by voters but struck down by the state Supreme Court. Medical dispensaries are operational.
Medical: 18+
Med: 3 oz per calendar year (increased amounts available with physician authorization)
Prohibited.
Medical patients may grow up to 3 plants if they live more than 50 miles from a dispensary.
Not allowed
Medical: standard state sales tax (4.5%) plus applicable municipal taxes.
Only South Dakota residents with medical cards may purchase. No out-of-state reciprocity.
Disclaimer: Cannabis laws change frequently. This information was last updated on January 15, 2026. Always verify current laws with official state sources before making any decisions. This guide is for informational purposes only and does not constitute legal advice.