Michelle
January 21, 2026
Great location and knowledgeable staff! Always got the best deals :)

Native Nations Cannabis Dispensary offers a selection of medical cannabis products to patients in South Dakota. They provide an online menu for convenient ordering.
4.5
465 reviews
Michelle
January 21, 2026
Great location and knowledgeable staff! Always got the best deals :)
Rmine
January 20, 2026
No matter which clerks I get, they are ALL so helpful & patient and KIND. I'm not ever dissatisfied by your customer service & product, THANK YOUUU !!!! I know I can always go there & get more than the budget I set for.myself. The rewards save me so.much!!!!
Dave Irwin
November 30, 2025
Friendly staff who knows what the good shit means. Great weed, great service, great price. Im a tourist here and I will be back when I come back.
Kay Lynn Brenner
October 9, 2025
I recently visited this dispensary in Flandreau and they were very very rude to me. Maybe it’s because I’m white. I don’t wanna make this a race issue,but they were so rude and the security guard literally put his hands on me and pulled me back. Who does that? I’ve been to plenty of dispensaries and it’s never been this bad.Plus your weed is GARBAGE! DO BETTER FLAUNDREA! Stop being racist to white people!
Nathan Witt
October 1, 2025
My car broke down and everyone there did the best they could to help me and the store is always clean and smells like home. Definitely stop by there if you’re ever around. Just an all around positive environment!!
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Only South Dakota residents with medical cards may purchase. No out-of-state reciprocity. Native Nations Cannabis Dispensary is a medical dispensary, so a valid medical card is required for purchases.
In South Dakota, medical customers can purchase up to 3 oz per calendar year (increased amounts available with physician authorization). Native Nations Cannabis Dispensary may have additional product-specific limits — check with the dispensary for details.
Native Nations Cannabis Dispensary is cash only. Check with the dispensary for nearby ATM locations.
Native Nations Cannabis Dispensary does not currently list delivery as an option. Available options include in-store, online ordering.
Native Nations Cannabis Dispensary is located at 1301 South Veterans Street, Flandreau, SD 57028. The dispensary is open 7 days a week. Hours vary by day — check the hours section above for today's schedule.
Last updated January 15, 2026
South Dakota legalized medical marijuana in 2020 through Initiated Measure 26. A simultaneous recreational measure (Amendment A) was passed by voters but struck down by the state Supreme Court. Medical dispensaries are operational.
Medical: 18+
Med: 3 oz per calendar year (increased amounts available with physician authorization)
Prohibited.
Medical patients may grow up to 3 plants if they live more than 50 miles from a dispensary.
Not allowed
Medical: standard state sales tax (4.5%) plus applicable municipal taxes.
Only South Dakota residents with medical cards may purchase. No out-of-state reciprocity.
Disclaimer: Cannabis laws change frequently. This information was last updated on January 15, 2026. Always verify current laws with official state sources before making any decisions. This guide is for informational purposes only and does not constitute legal advice.