Tena Fowlds
November 23, 2025
Very helpful for first timer. First to explain how everything worked and helped make some decisions based on my needs.

Genesis Farms Cannabis Dispensary is a leading medical cannabis provider in South Dakota, dedicated to delivering premium, patient-focused care. With 15 locations across the state, they offer high-quality medical cannabis products tailored to support qualifying patients.
4.9
141 reviews
Tena Fowlds
November 23, 2025
Very helpful for first timer. First to explain how everything worked and helped make some decisions based on my needs.
Cody Tomasi
October 21, 2025
Great selection. Great setup. Shop is very welcoming and the options are amazing. Yall do a great job of informing the patients of what they’re getting and also keeping each patient with the knowledge of what each product does. Very impressed with the business all around. Yall do a great job!
Kelly Shirey
September 16, 2025
Sales people were very courteous and professional. I was made to feel comfortable while inquiring and purchasing. Looking forward to next time.
Melissa Sigmund
August 9, 2025
Always great service. Wish they accepted cards, cash only, they do have an atm though. staff is always friendly and professional. Great selection of products.
Juice Pata
April 13, 2025
**Outstanding Service from Missy and Sierra at Genesis Farms I had the pleasure of being served by Missy and Sierra at Genesis Farms in Mitchell, South Dakota, and I cannot praise them enough! Both Missy and Sierra are exceptional bud tenders who truly go above and beyond to ensure a fantastic experience for their customers. What sets them apart is their extensive knowledge of the products available at the store. Missy and Sierra display a remarkable understanding of their craft. Their professionalism is matched by their friendly and approachable nature, making every visit a joy. If you're ever at Genesis Farms, make sure to stop by and see Missy and Sierra in action—you won't be disappointed. Their dedication to their work and their customers truly makes them stand out. Kudos to these two for making Genesis Farms such a welcoming and enjoyable place!
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Levoit Core 300-P
143 CFM · 219 sq ft
$80–$110

Coway Airmega AP-1512HH
246 CFM · 361 sq ft
$160–$210

Austin Air HM400
400 CFM · 1,500 sq ft
$475–$595
Only South Dakota residents with medical cards may purchase. No out-of-state reciprocity. Genesis Farms Cannabis Dispensary is a medical dispensary, so a valid medical card is required for purchases.
In South Dakota, medical customers can purchase up to 3 oz per calendar year (increased amounts available with physician authorization). Genesis Farms Cannabis Dispensary may have additional product-specific limits — check with the dispensary for details.
Genesis Farms Cannabis Dispensary is cash only. Check with the dispensary for nearby ATM locations.
Genesis Farms Cannabis Dispensary does not currently list delivery as an option. Available options include in-store.
Genesis Farms Cannabis Dispensary is located at 716 North Rowley Street, Mitchell, SD 57301. The dispensary is open 7 days a week. Hours vary by day — check the hours section above for today's schedule.
Last updated January 15, 2026
South Dakota legalized medical marijuana in 2020 through Initiated Measure 26. A simultaneous recreational measure (Amendment A) was passed by voters but struck down by the state Supreme Court. Medical dispensaries are operational.
Medical: 18+
Med: 3 oz per calendar year (increased amounts available with physician authorization)
Prohibited.
Medical patients may grow up to 3 plants if they live more than 50 miles from a dispensary.
Not allowed
Medical: standard state sales tax (4.5%) plus applicable municipal taxes.
Only South Dakota residents with medical cards may purchase. No out-of-state reciprocity.
Disclaimer: Cannabis laws change frequently. This information was last updated on January 15, 2026. Always verify current laws with official state sources before making any decisions. This guide is for informational purposes only and does not constitute legal advice.