Roy'zzz Premium Cannabis is a medical cannabis dispensary located in South Dakota, with locations in Yankton and Sioux Falls. They focus on providing a personalized cannabis experience with a variety of products tailored for active lifestyles, including edibles, concentrates, and flower.
4.9
329 reviews
Nikkia Childrey
January 31, 2026
Cyrus was a great help and a fantastic chat! He got me everything I needed and kept up a great conversation even showing me a trick when picking out glass. Overall it was an amazing experience at my favorite dispensary!
Cassidy Bingham
December 13, 2025
The employees are VERY helpful and outgoing. I love this dispensary over others because they seem a little more personal. I have my card for PTSD and I have severe physical symptoms. They were great helping me find some different things to help with relief. Great deals as well. Will be a repeat customer.
Mike H
December 13, 2025
Cyrus and Dan are the man. I came in for first time and immediately felt welcomed they were super helpful with my purchase!! These guys know their stuff and have top tier customer service 5 stars from me wish I could give 10!!! Keep up the great work fellas!!
Kayla Odell
December 8, 2025
Every time I have visited Roy'zzz I've had an absolutely AMAZING experience! The staff are super friendly, extremely knowledgeable, and incredibly helpful! I appreciate how patient they are, and I feel comfortable asking them any questions I have and for recommendations. They understand how overwhelming it can feel when someone walks into a dispensary for the first time, and getting to chat with them feels like talking with a friend. The store is BEAUTIFULLY kept, the prices are SUUUUPER reasonable & very affordable, and you can tell that the entire team truly enjoy being there. They take their time to make sure that all of your needs are met, your questions are answered, and never rush you. Big shout out to my budguide today, Cyrus! Thanks for be so awesome and patient with me, AND for helping me make the most out of the deals going on in the store! It was such a genuire pleasure getting to talk with you while you helped me. I can honestly say that visiting Roy'zzz and receiving such outstanding assistance and help made my day!!! I left the store with a pep in my step and a smile on my lips! All in all, I would ABSOLUTELY and HIGHLY recommend giving Roy'zzz a shot! They are DEFINITELY worth a visit!
Christina Rodeghier
September 3, 2025
I had a great first experience buying medical THC. Erica was so knowledgeable and personable. She listened to my needs and tailored up a starter pack for me! I will recommend Roy’zzz and be a return customer.
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Levoit Core 300-P
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Only South Dakota residents with medical cards may purchase. No out-of-state reciprocity. Roy'zzz Premium Cannabis is a medical dispensary, so a valid medical card is required for purchases.
In South Dakota, medical customers can purchase up to 3 oz per calendar year (increased amounts available with physician authorization). Roy'zzz Premium Cannabis may have additional product-specific limits — check with the dispensary for details.
Roy'zzz Premium Cannabis is cash only. Check with the dispensary for nearby ATM locations.
Roy'zzz Premium Cannabis does not currently list delivery as an option. Available options include in-store.
Roy'zzz Premium Cannabis is located at 2520 South Louise Avenue, Sioux Falls, SD 57106. The dispensary is open 7 days a week. Hours vary by day — check the hours section above for today's schedule.
Sioux Falls, SD
Sioux Falls, SD
Sioux Falls, SD
Last updated January 15, 2026
South Dakota legalized medical marijuana in 2020 through Initiated Measure 26. A simultaneous recreational measure (Amendment A) was passed by voters but struck down by the state Supreme Court. Medical dispensaries are operational.
Medical: 18+
Med: 3 oz per calendar year (increased amounts available with physician authorization)
Prohibited.
Medical patients may grow up to 3 plants if they live more than 50 miles from a dispensary.
Not allowed
Medical: standard state sales tax (4.5%) plus applicable municipal taxes.
Only South Dakota residents with medical cards may purchase. No out-of-state reciprocity.
Disclaimer: Cannabis laws change frequently. This information was last updated on January 15, 2026. Always verify current laws with official state sources before making any decisions. This guide is for informational purposes only and does not constitute legal advice.
