Akilah Smith
January 29, 2026
The absolute best dispensary I have ever stepped into!! I drove 30 mins from my hometown to visit and was not disappointed, already planning my next visit

Mary Jane & Herb's is a medical cannabis dispensary located in Hattiesburg, Mississippi, dedicated to serving registered medical cannabis patients. The dispensary emphasizes the importance of cannabis as a therapeutic option for various medical conditions, reflecting a rich family heritage in the cannabis industry.
Mary Jane & Herb's is a medical-only dispensary. You must have a valid Mississippi medical marijuana card to purchase here. Get approved online in about 20 minutes.
4.6
57 reviews
Akilah Smith
January 29, 2026
The absolute best dispensary I have ever stepped into!! I drove 30 mins from my hometown to visit and was not disappointed, already planning my next visit
Heather Moore
December 24, 2025
Being a disabled person this place is amazing. It took my doctor 2 years to talk me into trying this stuff. I have CRPS and it's rough. So imagine my surprise when not only did they have what I needed for pain anxiety and depression they also are very knowledgeable. Which for me was very important. I wasn't looking to get high but get off the medications I've been prescribed for years. I do believe this will to the trick. It's a cash only place and the prices are good I believe, plus I get a military discount so that helps. The quality is very good. Check out was super easy and the staff are wonderful. They have everything from edibles to flower. Nice clean and well organized store. I found everything I was looking for.
Jim penoza
December 23, 2025
They are Really Good People in the Hattiesburg location, Great selection, Very Knowledgeable and Friendly and have treats for our pets. My little Penny loves to go and see everyone and get a treat or 4 or 5 ๐ ๐คฃ ๐ There the Best โค๏ธ
Jamie Alaizah Roberts
September 27, 2025
Update: (This is their 2nd strike after a bad visit in August 2024) Returned a few days later after a year later second chance visit with Landry, Jena & John which was good, only to be met with a scam. The buy one, get one half off flower special is a false lure to get you in their store then they hit you with the REAL special which is 20% off flower. The two guys who seem to be managers love to argue with customers and have ZERO respect, Jena was there but basically hid cause she knew I caught onto their buy one flower, get one flower half off special which hides their REAL special of 20% off flower. The tall younger guy basically called me stupid because I wasn't understanding his example of math which used a item of the most expensive price ($100) to make his point and to further hide the scam they advertising when we discussing a $35 item, he also stated his math assessment shows they favor the rich & the poor at the same time which NO price that is high would favor the poor, it would only favor the rich. They take the meaning of "high" LITERAL with their high prices, seems like they making customers pay for their fancy inside cracker barrell look & fancy display cases . After all that with the one guy, the older tall guy ask for advice on my interpretation of buy one, get one half off then when I went to give it, he overtalks me like my opinion no longer matter and even once I said I was done. He still kept arguing until I told him that disrespecting the customer after they say they are done is bad for business and it seemed like they are desperate for business with his behavior. In the end, I left angry with the one item I didn't come for but I needed something after paying for a uber, which they added 10% off as a bribe to get me to come back, seems like when they see you pull up in fancy looking Uber's, it leads them to believe you got money to blow and I say that because of the comment the tall young guy made about my uber driver having a very nice car. Now I know why their parking lot is always so empty and why my friends do not shop here any longer. This place is CLEARLY set up for the rich and to take as much money from the poor as they possibly can. NO MORE CHANCES for this place, after a second failed visit
Charles Taylor
September 26, 2025
Very cozy and charming atmosphere inside. Almost like a CrackerBarrell store feel. Landry was very knowledgeable and a great asset to the store. Look forward to visiting again next time I'm in Hattiesburg
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Only Mississippi residents with a valid medical cannabis card may purchase. No out-of-state reciprocity. Mary Jane & Herb's is a medical dispensary, so a valid medical card is required for purchases.
In Mississippi, medical customers can purchase up to 3 oz per month (3.5g per day equivalent); terminally ill patients may purchase up to 6 oz per month. Mary Jane & Herb's may have additional product-specific limits โ check with the dispensary for details.
Mary Jane & Herb's is cash only. Check with the dispensary for nearby ATM locations.
Mary Jane & Herb's does not currently list delivery as an option. Available options include in-store.
Mary Jane & Herb's is located at 135 Thornhill Drive, Hattiesburg, MS 39402. The dispensary is open 7 days a week. Hours vary by day โ check the hours section above for today's schedule.
You need a Mississippi medical marijuana card to purchase from dispensaries in this state. The whole process can be completed online in about 20 minutes from home.
โ Board-certified physicians ย ยทย โ 4.8โ rated ย ยทย โ 500,000+ patients approved
Get My Mississippi Medical CardLast updated January 15, 2026
Mississippi legalized medical cannabis in 2022 through SB 2095 (the Mississippi Medical Cannabis Act). Licensed dispensaries began selling in early 2024. Recreational cannabis remains illegal.
Medical: 18+
Med: 3 oz per month (3.5g per day equivalent); terminally ill patients may purchase up to 6 oz per month
Prohibited. Medical cannabis may only be consumed at a private residence. Smoking is allowed for medical patients.
Not allowed.
Not allowed
Medical cannabis is subject to a 7% state sales tax.
Only Mississippi residents with a valid medical cannabis card may purchase. No out-of-state reciprocity.
Disclaimer: Cannabis laws change frequently. This information was last updated on January 15, 2026. Always verify current laws with official state sources before making any decisions. This guide is for informational purposes only and does not constitute legal advice.