H
Holly Reeves
January 19, 2026
5.0
If I could give more than 5 stars I would!! This is my favorite dispensary. The vibes are immaculate and Rowan is always so helpful and such a beautiful light to the world. Everyone is so helpful and kind. 10/10.
Medical$$
Southern Sky Wellness Dispensary Pearl
4.9(187)
Southern Sky Wellness Dispensary in Pearl, MS is a medical cannabis dispensary dedicated to providing high-quality cannabis products and personalized service to meet wellness needs. They offer a variety of products including flower, pre-rolls, edibles, concentrates, and CBD options, all while focusing on education and community support.
Medical card required in Mississippi
Southern Sky Wellness Dispensary Pearl is a medical-only dispensary. You must have a valid Mississippi medical marijuana card to purchase here. Get approved online in about 20 minutes.
Products & Menu
FlowerPre-RollsEdiblesConcentratesTincturesTopicalsAccessories
THC:21%–27%
CBD:0%–20%
Features & Amenities
Fulfillment
🏪In-Store
Payment
💵Cash
Medical
🏥Accepts Medical Card
Shopper Type
🌱Beginner-Friendly
Access
♿Wheelchair Accessible
Hours
Monday9:00 AM – 7:00 PM
Tuesday9:00 AM – 7:00 PM
Wednesday9:00 AM – 7:00 PM
Thursday9:00 AM – 7:00 PM
Friday9:00 AM – 8:00 PM
Saturday(Today)9:00 AM – 8:00 PM
Sunday10:00 AM – 5:00 PM
Reviews (187)
4.9
4.9
187 reviews
T
Thomas Mahoney
January 18, 2026
5.0
I visit Southern Sky regularly and it is one of my favorite dispensaries, the aesthetic is very warm and welcoming. The staff are all very attentive, passionate, and dedicated. Southern Sky has some of the best customer service I’ve experienced, the budtenders are all very knowledgeable. Shelby is the budtender I’ve interacted with most, she’s helped numerous times able to offer multiple options based on whatever I may be looking for, she understands a lot about concentrates and has helped me find products I previously might have overlooked. Overall every experience has been great, the staff are all wonderful, and I would recommend this place to anyone looking for quality care
t
trey wilkerson
January 15, 2026
5.0
Awesome staff, full of amazing people! Great pricing and full of variety. I love dealing with Lexi or Meredith they will never disappoint. AND neither does their products.
M
Matthew Scott Watson
November 4, 2025
5.0
Southern Sky is amazing! The people, the products, and the knowledge they have is so wonderful. They were one of my first experiences as a patient, and they have remained one of the best! You really do feel at home here. Lexi was the first person to help me and my wife/caregiver, and she was so awesome! We truly consider her and literally everyone there friends for life. (I would name everyone, but I just know I’d leave someone out!) Don’t miss out on Southern Sky!
5
50-Superhero
February 16, 2024
5.0
My experience at Southern Sky Wellness Dispensary was nothing short of amazing. From the moment I arrived, I was warmly welcomed by the attentive staff and enveloped in a serene, calming atmosphere. I can’t say enough good things about Southern Sky and their incredible team. Also, prices are reasonable for the quality you get. They are currently offering 30% Off of any first time patients purchase of entire lot (6 items), they also offer a 20% Veteran discount to thank you for your service.
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Frequently Asked Questions About Southern Sky Wellness Dispensary Pearl
Can tourists buy from Southern Sky Wellness Dispensary Pearl?
Only Mississippi residents with a valid medical cannabis card may purchase. No out-of-state reciprocity. Southern Sky Wellness Dispensary Pearl is a medical dispensary, so a valid medical card is required for purchases.
How much can you buy at Southern Sky Wellness Dispensary Pearl?
In Mississippi, medical customers can purchase up to 3 oz per month (3.5g per day equivalent); terminally ill patients may purchase up to 6 oz per month. Southern Sky Wellness Dispensary Pearl may have additional product-specific limits — check with the dispensary for details.
Is Southern Sky Wellness Dispensary Pearl cash only?
Southern Sky Wellness Dispensary Pearl is cash only. Check with the dispensary for nearby ATM locations.
Does Southern Sky Wellness Dispensary Pearl offer delivery?
Southern Sky Wellness Dispensary Pearl does not currently list delivery as an option. Available options include in-store.
What are Southern Sky Wellness Dispensary Pearl's hours?
Southern Sky Wellness Dispensary Pearl is located at 422 Riverwind Drive, Pearl, MS 39208. The dispensary is open 7 days a week. Hours vary by day — check the hours section above for today's schedule.
Get Your Mississippi Medical Card Online
You need a Mississippi medical marijuana card to purchase from dispensaries in this state. The whole process can be completed online in about 20 minutes from home.
✓ Board-certified physicians · ✓ 4.8★ rated · ✓ 500,000+ patients approved
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Cannabis Laws in Mississippi
Last updated January 15, 2026
Mississippi legalized medical cannabis in 2022 through SB 2095 (the Mississippi Medical Cannabis Act). Licensed dispensaries began selling in early 2024. Recreational cannabis remains illegal.
Minimum Age
Medical: 18+
Purchase Limits
Med: 3 oz per month (3.5g per day equivalent); terminally ill patients may purchase up to 6 oz per month
Public Consumption
Prohibited. Medical cannabis may only be consumed at a private residence. Smoking is allowed for medical patients.
Home Growing
Not allowed.
Delivery
Not allowed
Tax Info
Medical cannabis is subject to a 7% state sales tax.
Visitor & Tourist Rules
Only Mississippi residents with a valid medical cannabis card may purchase. No out-of-state reciprocity.
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Disclaimer: Cannabis laws change frequently. This information was last updated on January 15, 2026. Always verify current laws with official state sources before making any decisions. This guide is for informational purposes only and does not constitute legal advice.