The Dispensary on Main is Galesburg's premier destination for high-quality THCa, CBD, and CBG products. With a focus on wellness and community, they offer a curated selection of cannabis products in a cozy atmosphere, making it accessible for both seasoned enthusiasts and newcomers.
Medical patients skip recreational taxes, get higher purchase limits, and can shop at age 18+. Most people get approved online in about 20 minutes.
4.7
56 reviews
Olivia Thatch
January 11, 2026
Walked in on a whim, and had a wonderful experience. Friendly Budtenders, chill atmosphere, fair and honest prices, tons of flower choices, you get to inspect the products before purchase. Plan to go back tenfold.
jackson jackson
December 29, 2025
passing through on the train and this place was amazing. friendly, good prices, good product 10/10
Matthew Needham
December 17, 2025
Don't waste your time with NTI anymore, this place is much better. I'm not sure what her name is, but the person behind the counter I talked to when I came in was welcoming and knowledgeable, and explained not only how they operate and how they cultivate the products, but also regulations and legislation related to thc and hemp products. The value here is much better than NTI. I'll be saving about 75 bucks a month thanks to this dispo, plus you can mix strains instead of only being able to buy one strain at a time. It's probably the best weed I've ever smoked too. It's basically premium homegrown cannabis. No added chemicals or pesticides are used, which really enhances the buzz and the terepenes. The buzz is clean and relaxed me without feeling glued to the couch, and the terpene effects are noticeable. It's the only place to go in Galesburg at this point, excellent place to go.
Kaylee Haynes
November 24, 2025
I’ve always had such a great experience in this store! Extremely friendly and knowledgeable staff, great prices and they always have great recommendations!
Tracy (Dementia)
August 10, 2025
Love this place,I prefer this reefer. Great price,environment and staff.Always can't wait to come back and try another batch.
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Levoit Core 300-P
143 CFM · 219 sq ft
$80–$110
Coway Airmega AP-1512HH
246 CFM · 361 sq ft
$160–$210
Austin Air HM400
400 CFM · 1,500 sq ft
$475–$595
Tourists 21+ can purchase recreational cannabis but are limited to half the resident amounts (15g flower, 2.5g concentrate, 250mg THC edibles). A valid government-issued ID from any state is accepted. The Dispensary on Main is a recreational & medical dispensary, so no medical card is needed for adult-use purchases.
In Illinois, recreational customers can purchase up to Residents: 30g flower, 5g concentrate, 500mg THC in edibles. Non-residents: half those amounts (15g, 2.5g, 250mg).. The Dispensary on Main may have additional product-specific limits — check with the dispensary for details.
The Dispensary on Main accepts cash as well as Debit.
The Dispensary on Main does not currently list delivery as an option. Available options include in-store.
The Dispensary on Main is located at 235 East Main Street, Galesburg, IL 61401. The dispensary is open 7 days a week. Hours vary by day — check the hours section above for today's schedule.
Medical patients in Illinois save ~9% on cannabis purchases, get higher purchase limits, and access dispensaries at age 18+. Most patients can get approved online in about 20 minutes.
✓ Board-certified physicians · ✓ 4.8★ rated · ✓ 500,000+ patients approved
Get My Illinois Medical CardLast updated January 15, 2026
Illinois legalized recreational cannabis in 2019 through the Cannabis Regulation and Tax Act, becoming the first state to do so through the legislature (rather than ballot measure). Recreational sales began January 1, 2020. Illinois also has a medical program dating back to 2013.
Recreational: 21+
Medical: 18+
Rec: Residents: 30g flower, 5g concentrate, 500mg THC in edibles. Non-residents: half those amounts (15g, 2.5g, 250mg).
Med: 2.5 oz of flower per 14-day period
Prohibited in most public places. Cannot consume in vehicles, on school grounds, near anyone under 21, or where smoking is banned. Some municipalities may allow consumption lounges.
Medical patients only — up to 5 plants per household in a locked, enclosed space. Recreational users may not grow at home.
Allowed
Recreational cannabis is taxed based on THC content: 10% for products with ≤35% THC (flower), 20% for infused products, and 25% for products with >35% THC (concentrates). Plus 6.25% state sales tax and local taxes (up to 3%). Medical cannabis is taxed at 1% state sales tax only.
Tourists 21+ can purchase recreational cannabis but are limited to half the resident amounts (15g flower, 2.5g concentrate, 250mg THC edibles). A valid government-issued ID from any state is accepted.
Disclaimer: Cannabis laws change frequently. This information was last updated on January 15, 2026. Always verify current laws with official state sources before making any decisions. This guide is for informational purposes only and does not constitute legal advice.
