High Profile Cannabis Shop in Columbia, Missouri, offers a wide selection of premium medical and recreational marijuana products. With a focus on quality and customer experience, they provide a variety of options including flower, pre-rolls, edibles, and concentrates, along with knowledgeable budtenders to assist customers.
1500 Interstate 70 Drive Southwest
Columbia, MO 65203
$$ · Recreational & Medical
Medical patients skip recreational taxes, get higher purchase limits, and can shop at age 18+. Most people get approved online in about 20 minutes.
4.8
1,708 reviews
Sam Mykel
January 6, 2026
My first experience at High Profile was great! The staff was super friendly, helpful, and they made sure to let me know about any discounts I qualified for. Don Carlos was an excellent budtender. Not only did he show me some of the store’s newest products, but he made me feel comfortable in a new dispensary. Overall, I had a great experience and am looking forward to my next visit!
Christine Kay
December 19, 2025
She was the sweetest!!!! Give her a raise bc she deserves it!!!! She’s so beautiful too. Did a wonderful job. Best employee ever!!! 10/10 experience. I’d come back again just for her!!! She’s so cool!!!
serenity lipcamon
December 6, 2025
had a fantastic experience! I was greeted as soon as I walked in, and the receptionist was very pleasant and welcoming. My budtender was patient, knowledgeable, and extremely helpful in guiding me to exactly what I needed. Overall, top-tier service and maximum satisfaction. Highly recommend!
Mark Samson
October 29, 2025
I was extremely happy with my last purchase. Not only did I get a discount, I also received great service from cashier 96985. Even without a discount, their prices are quite reasonable. They also have a good selection of products. The other thing I liked is that under most cases, you can get in quickly, make your selection, and get on with life to go home or wherever you are going to enjoy your purchase. Please Drive Safely!!
Ssj Llama
October 21, 2025
I paid for 7g of flower and got this instead. The person behind the counter put the bowl on the scale without resetting it and gave me way less than 7. This is a scam very disappointed. They also said they would weigh it, took it into the back, but came back and said they couldn't because we "might have tampered with it". Probably because it is very clearly a lot less than 7 gs and he wasn't willing to admit it
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Tourists 21+ can purchase recreational cannabis with valid ID. High Profile of Columbia Dispensary is a recreational & medical dispensary, so no medical card is needed for adult-use purchases.
In Missouri, recreational customers can purchase up to 3 oz of flower per transaction. High Profile of Columbia Dispensary may have additional product-specific limits — check with the dispensary for details.
High Profile of Columbia Dispensary accepts cash as well as Debit, ATM On-Site. An ATM is available on-site.
High Profile of Columbia Dispensary does not currently list delivery as an option. Available options include in-store, curbside pickup.
High Profile of Columbia Dispensary is located at 1500 Interstate 70 Drive Southwest, Columbia, MO 65203. The dispensary is open 7 days a week. Hours vary by day — check the hours section above for today's schedule.
Medical patients in Missouri save ~6% on cannabis purchases, get higher purchase limits, and access dispensaries at age 18+. Most patients can get approved online in about 20 minutes.
✓ Board-certified physicians · ✓ 4.8★ rated · ✓ 500,000+ patients approved
Get My Missouri Medical Card
Columbia, MO
Columbia, MO
Columbia, MO
Last updated January 15, 2026
Missouri legalized recreational cannabis in November 2022 through Amendment 3, with recreational sales beginning February 3, 2023. Adults 21+ can purchase from licensed dispensaries. Missouri also expunged past cannabis convictions as part of the amendment. Medical cannabis has been available since 2018.
Recreational: 21+
Medical: 18+
Rec: 3 oz of flower per transaction
Med: 6 oz per month
Prohibited in public places. Only allowed on private property with owner permission.
Medical patients may grow up to 6 flowering, 6 vegetative, and 6 clones/seedlings. Recreational home growing is allowed for adults 21+ with a personal cultivation license ($100).
Allowed
Recreational: 6% state excise tax plus 4.225% state sales tax plus local taxes. Medical: 4% state tax.
Tourists 21+ can purchase recreational cannabis with valid ID.
Disclaimer: Cannabis laws change frequently. This information was last updated on January 15, 2026. Always verify current laws with official state sources before making any decisions. This guide is for informational purposes only and does not constitute legal advice.
